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A rectangular white casserole dish of baked Buffalo Chicken Mac and Cheese with a golden panko and blue cheese topping.

Buffalo Chicken Mac and Cheese

Rebecca Blumer
This Buffalo Chicken Mac and Cheese combines tender chicken and pasta in a creamy, spicy cheese sauce. It's baked in a casserole with a crunchy panko-bleu cheese topping for a satisfying and flavorful meal.
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Prep Time 20 minutes
Cook Time 45 minutes
Total Time 1 hour 5 minutes
Course Dinner, Lunch, Main Course
Cuisine American
Servings 8 servings
Calories 1127 kcal

Equipment

  • Large stock pot
  • Skillet
  • 13x9” Casserole Dish

Ingredients
 

For the Macaroni

  • 8 oz elbow macaroni cooked and drained
  • 1 tbsp olive oil

Buffalo Chicken Mixture

  • 4 tbsp butter
  • 1 onion medium, chopped
  • 3 celery stalks chopped
  • 4 garlic cloves minced
  • 1/2 tsp salt
  • 1/2 tsp black pepper
  • 1/2 cup hot sauce I use Franks
  • 4 cups rotisserie chicken chopped

Cheese Sauce

  • 2 tbsp all purpose flour
  • 2 tbsp butter
  • 2 1/2 cups half and half
  • 1/4 cup hot sauce I use Franks
  • 1 tbsp dijon mustard
  • 2 cups cheddar cheese shredded
  • 2 cups mozzarella cheese shredded
  • 1 cup sour cream

Topping

  • 1 cup Panko bread crumbs
  • 2 tbsp butter melted
  • 1/2 cup bleu cheese crumbles
  • 1/4 cup parsley chopped, loosely packed

Instructions
 

  • Heat the oven to 350°F, then stir the 2 tbsp butter (melted), 1 cup Panko bread crumbs, 1/2 cup bleu cheese crumbles, and 1/4 cup parsley chopped (loosely packed) together in a small bowl. The topping should look evenly moistened with loose crumbs, not pasty or packed.
  • Boil the 8 oz elbow macaroni in heavily salted water following the package directions, then drain and toss it with 1 tbsp olive oil. Cook the pasta to al dente so it stays tender in the oven instead of turning soft.
  • Melt 4 tbsp butter in a large skillet over medium heat, then cook the onion and celery for 5 minutes before adding the garlic, 1/2 tsp salt, and 1/2 tsp black pepper for 2 minutes more. The vegetables should be soft and translucent, not browned, and the garlic should smell fragrant.
  • Stir in the 1/2 cup hot sauce and 4 cups rotisserie chicken (chopped), then cook for 2 to 3 minutes and set the mixture aside. The buffalo coating should lightly cling to the chicken and look a bit thicker than when it first went in.
  • In the same skillet, melt 2 tbsp butter over medium heat, whisk in the 2 tbsp all purpose flour, and keep whisking for 1 minute. Stir constantly so the flour loses its raw taste without taking on much color.
  • Pour in the 2 1/2 cups half and half, whisk until smooth, then add the 1/4 cup hot sauce and 1 tbsp dijon mustard and lower the heat to a simmer for 4 minutes. The sauce is ready for cheese when it thickens enough to coat the back of a spoon.
  • Stir in the 1 cup sour cream, 2 cups shredded cheddar cheese, and 2 cups shredded mozzarella cheese until fully melted. Keep the heat low and stop when the sauce looks smooth, glossy, and creamy.
  • Transfer the macaroni to a greased 13x9-inch casserole dish, add the chicken mixture, pour the cheese sauce over the top, and stir everything together well. Make sure the pasta is fully coated so the casserole bakes up creamy from edge to center.
  • Cover the dish with aluminum foil and bake for 40 minutes, then uncover, add the crumb topping, and bake 5 minutes more. The top should turn golden and crunchy while the filling bubbles around the edges.

Notes

Smooth Sauce Tip: For the smoothest sauce, grate cheese from a block. Pre-shredded cheese can contain anti-caking agents that make the sauce grainy.
Pasta Prep: Cook the macaroni only to al dente. It will continue to cook in the oven, and this prevents it from becoming mushy.
Storage and Reheating: Store leftovers covered in the refrigerator. Reheat on the stovetop with a splash of milk to restore creaminess, or covered in the oven.
Make-Ahead: To make ahead, assemble the casserole without the topping and refrigerate. Add the crumb topping just before baking to ensure it stays crunchy.
Nutrition information is an estimate based on common ingredients and serving sizes. Values may vary depending on brands, portions, and substitutions.

Nutrition

Calories: 1127kcalCarbohydrates: 36gProtein: 108gFat: 59gSaturated Fat: 30gCholesterol: 365mgSodium: 1299mgPotassium: 200mgFiber: 2gSugar: 3gVitamin A: 100IUVitamin C: 5mgCalcium: 300mgIron: 2mg
Keyword baked mac and cheese, Buffalo Chicken Mac and Cheese, Comfort Food, spicy pasta
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